From this page you can access a list of FAQ's related to hardware issues, to access the information just click on the page indicated on the left hand side
If you need to consider using multiple devices or modules to create a larger matrix here is a useful guide to how to do - assuming you cannot use the better alternative of a fully integrated design
The PXI standard requires the chassis to be able to dissipate an average of 25W per slot. For some types of switching there are circumstances where this can be exceeded. This page will provide some help if you have thermal issues.